I recently played Where in the World is Carmen Sandiego? and Hugo’s House of Horrors! Carmen Sandiego was a lot of fun. Hugo was… not as good as I remembered, but still worth playing for nostalgia’s sake.
I forgot to mention the King’s Quest series as well. Those were big favorites, of course. A couple of months ago, I replayed KQVII, which I know can be divisive but remains my favorite.